VARIOUS ALLELES OF HSF HEAT-SHOCK TRANSCRIPTION FACTOR OF DROSOPHILA MELANOGASTER INCREASE VIABILITY OF ITS CARRIERS IN UNFAVORABLE ENVIRONMENTS

N. Ya Weisman, M. B. Evgen'ev, M. D. Golubovsky

Research output: Contribution to journalArticlepeer-review

Abstract

We found increased viability in heterozygous carriers of hsf heat shock transcription factor n comparison with wild type. The effect depends on temperature, sex and direction of crosses. Viability effect is more evident in conditions of soft temperature stress. The males are more sensitive. The maternal effect is observed: if hsf*allele came from mother, the viability effect is stronger. The survival curves of heterozygotes on hsf-1 and hsf-4 alleles are similar in spite of HSF-4 protein is slightly active on normal temperature.

Original languageEnglish
Pages (from-to)248-256
Number of pages9
JournalAdvances in gerontology = Uspekhi gerontologii / Rossiiskaia akademiia nauk, Gerontologicheskoe obshchestvo
Volume28
Issue number2
StatePublished - 2015

ASJC Scopus subject areas

  • General Medicine

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