Under-diagnosis of SARS-CoV-2 infections among children aged 0-15 years, a nationwide seroprevalence study, Israel, January 2020 to March 2021

Victoria Indenbaum; Yaniv Lustig; Ella Mendelson; Yael Hershkovitz; Aharona Glatman-Freedman; Lital Keinan-Boker; Ravit Bassal

doi:10.2807/1560-7917.ES.2021.26.48.2101040

Under-diagnosis of SARS-CoV-2 infections among children aged 0-15 years, a nationwide seroprevalence study, Israel, January 2020 to March 2021

Victoria Indenbaum, Yaniv Lustig, Ella Mendelson, Yael Hershkovitz, Aharona Glatman-Freedman, Lital Keinan-Boker, Ravit Bassal

School of Public Health

Research output: Contribution to journal › Article › peer-review

Abstract

Until recently, children and adolescents were not eligible for COVID-19 vaccination. They may have been a considerable source of SARS-CoV-2 spread. We evaluated SARS-CoV-2 IgG antibody seroprevalence in Israeli children aged 0-15 years from January 2020 to March 2021. Seropositivity was 1.8-5.5 times higher than COVID-19 incidence rates based on PCR testing. We found that SARS-CoV-2 infection among children is more prevalent than previously thought and emphasise the importance of seroprevalence studies to accurately estimate exposure.

Original language	English
Article number	2101040
Journal	Eurosurveillance
Volume	26
Issue number	48
DOIs	https://doi.org/10.2807/1560-7917.ES.2021.26.48.2101040
State	Published - 2 Dec 2021

Bibliographical note

Publisher Copyright:
© 2021 European Centre for Disease Prevention and Control (ECDC). All rights reserved.

ASJC Scopus subject areas

Epidemiology
Public Health, Environmental and Occupational Health
Virology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.2807/1560-7917.ES.2021.26.48.2101040

Cite this

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AU - Mendelson, Ella

AU - Hershkovitz, Yael

AU - Glatman-Freedman, Aharona

AU - Keinan-Boker, Lital

AU - Bassal, Ravit

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AB - Until recently, children and adolescents were not eligible for COVID-19 vaccination. They may have been a considerable source of SARS-CoV-2 spread. We evaluated SARS-CoV-2 IgG antibody seroprevalence in Israeli children aged 0-15 years from January 2020 to March 2021. Seropositivity was 1.8-5.5 times higher than COVID-19 incidence rates based on PCR testing. We found that SARS-CoV-2 infection among children is more prevalent than previously thought and emphasise the importance of seroprevalence studies to accurately estimate exposure.

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Under-diagnosis of SARS-CoV-2 infections among children aged 0-15 years, a nationwide seroprevalence study, Israel, January 2020 to March 2021

Abstract

Bibliographical note

ASJC Scopus subject areas

UN SDGs

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