TreeScan: A bioinformatic application to search for genotype/phenotype associations using haplotype trees

David Posada, Taylor J. Maxwell, Alan R. Templeton

Research output: Contribution to journalArticlepeer-review

Abstract

Summary: We present the software implementation of the tree scanning method to detect associations between genetic haplotypes and quantitative traits, utilizing the evolutionary history of the haplotypes, in samples of unrelated individuals.

Original languageEnglish
Pages (from-to)2130-2132
Number of pages3
JournalBioinformatics
Volume21
Issue number9
DOIs
StatePublished - 1 May 2005
Externally publishedYes

Bibliographical note

Funding Information:
Part of this work was done at Variagenics, Inc (Cambridge, MA, USA). We thank Vincent Stanton, Jr, Daniel Chasman, Lakshman Subrahmanyan and Carsten Wiuf for the helpful discussions. Financial support from the Burroughs Wellcome Fund Innovation Award in Functional Genomics 100133, an NSF predoctoral fellowship award to T. J. M., and the National Institutes of Health grant GM65509 are gratefully acknowledged.

ASJC Scopus subject areas

  • Statistics and Probability
  • Biochemistry
  • Molecular Biology
  • Computer Science Applications
  • Computational Theory and Mathematics
  • Computational Mathematics

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