Treatment of Porphyric Convulsions with Magnesium Sulfate

M. Sadeh, I. Blatt, G. Martonovits, A. Karni, Y. Goldhammer

Research output: Contribution to journalArticlepeer-review

Abstract

Summary: We report a 16‐year‐old girl with acute intermittent porphyria who had abdominal pain, generalized tonic‐clonic and simple partial seizures, and inappropriate antidiuretic hormone secretion. Because most antiepileptic drugs are contraindicated in porphyria, she was treated with magnesium sulfate i.v. Soon after starting treatment, seizures stopped, returned, and then again responded in several trials with discontinuation and reinstitution of i.v. magnesium sulfate. Our experience encourages the use of magnesium sulfate for treatment of seizures in patients with porphyria.

Original languageEnglish
Pages (from-to)712-715
Number of pages4
JournalEpilepsia
Volume32
Issue number5
DOIs
StatePublished - Oct 1991
Externally publishedYes

Keywords

  • Acute intermittent porphyria
  • Epilepsy
  • Magnesium sulfate

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

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