Treatment of Porphyric Convulsions with Magnesium Sulfate

M. Sadeh; I. Blatt; G. Martonovits; A. Karni; Y. Goldhammer

doi:10.1111/j.1528-1157.1991.tb04714.x

Treatment of Porphyric Convulsions with Magnesium Sulfate

M. Sadeh, I. Blatt, G. Martonovits, A. Karni, Y. Goldhammer

Research output: Contribution to journal › Article › peer-review

Abstract

Summary: We report a 16‐year‐old girl with acute intermittent porphyria who had abdominal pain, generalized tonic‐clonic and simple partial seizures, and inappropriate antidiuretic hormone secretion. Because most antiepileptic drugs are contraindicated in porphyria, she was treated with magnesium sulfate i.v. Soon after starting treatment, seizures stopped, returned, and then again responded in several trials with discontinuation and reinstitution of i.v. magnesium sulfate. Our experience encourages the use of magnesium sulfate for treatment of seizures in patients with porphyria.

Original language	English
Pages (from-to)	712-715
Number of pages	4
Journal	Epilepsia
Volume	32
Issue number	5
DOIs	https://doi.org/10.1111/j.1528-1157.1991.tb04714.x
State	Published - Oct 1991
Externally published	Yes

Keywords

Acute intermittent porphyria
Epilepsy
Magnesium sulfate

ASJC Scopus subject areas

Neurology
Clinical Neurology

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10.1111/j.1528-1157.1991.tb04714.x

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abstract = "Summary: We report a 16‐year‐old girl with acute intermittent porphyria who had abdominal pain, generalized tonic‐clonic and simple partial seizures, and inappropriate antidiuretic hormone secretion. Because most antiepileptic drugs are contraindicated in porphyria, she was treated with magnesium sulfate i.v. Soon after starting treatment, seizures stopped, returned, and then again responded in several trials with discontinuation and reinstitution of i.v. magnesium sulfate. Our experience encourages the use of magnesium sulfate for treatment of seizures in patients with porphyria.",

keywords = "Acute intermittent porphyria, Epilepsy, Magnesium sulfate",

author = "M. Sadeh and I. Blatt and G. Martonovits and A. Karni and Y. Goldhammer",

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AU - Sadeh, M.

AU - Blatt, I.

AU - Martonovits, G.

AU - Karni, A.

AU - Goldhammer, Y.

PY - 1991/10

Y1 - 1991/10

N2 - Summary: We report a 16‐year‐old girl with acute intermittent porphyria who had abdominal pain, generalized tonic‐clonic and simple partial seizures, and inappropriate antidiuretic hormone secretion. Because most antiepileptic drugs are contraindicated in porphyria, she was treated with magnesium sulfate i.v. Soon after starting treatment, seizures stopped, returned, and then again responded in several trials with discontinuation and reinstitution of i.v. magnesium sulfate. Our experience encourages the use of magnesium sulfate for treatment of seizures in patients with porphyria.

AB - Summary: We report a 16‐year‐old girl with acute intermittent porphyria who had abdominal pain, generalized tonic‐clonic and simple partial seizures, and inappropriate antidiuretic hormone secretion. Because most antiepileptic drugs are contraindicated in porphyria, she was treated with magnesium sulfate i.v. Soon after starting treatment, seizures stopped, returned, and then again responded in several trials with discontinuation and reinstitution of i.v. magnesium sulfate. Our experience encourages the use of magnesium sulfate for treatment of seizures in patients with porphyria.

KW - Acute intermittent porphyria

KW - Epilepsy

KW - Magnesium sulfate

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JO - Epilepsia

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ER -

Treatment of Porphyric Convulsions with Magnesium Sulfate

Abstract

Keywords

ASJC Scopus subject areas

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