Transvaginal sonography—detection of findings suggestive of fetal chromosomal anomalies in the first and early second trimesters

Moshe Bronshtein, Zeev Blumenfeld

Research output: Contribution to journalArticlepeer-review

Abstract

Over a 4‐year period, 14 dyskaryotic fetuses were diagnosed by amniocentesis, performed after early detection of malformations using transvaginal sonography (TVS). These 14 dyskaryotic fetuses were detected out of 4878 sonographic screenings performed by TVS between 9 and 16 weeks' gestation. Twenty‐eight per cent of the referrals were at high risk and 72 per cent were at low risk for fetal malformations. Two hundred and twenty‐nine fetuses (4.7 per cent) of the screened population had 265 anomalies, 39 per cent of them being transient. In 7 of the 14 dyskaryotic fetuses (50 per cent), the sonographically detected anomalies were transient, being undetected by follow‐up sonographic screenings at later gestational ages (⩾18 weeks). Postponing the first sonographic scan aimed at malformation detection to a later gestational age may lead to transient anomalies and their associated dyskaryosis being missed.

Original languageEnglish
Pages (from-to)587-593
Number of pages7
JournalPrenatal Diagnosis
Volume12
Issue number7
DOIs
StatePublished - Jul 1992
Externally publishedYes

Keywords

  • Chromosomal abnormality
  • Fetal malformations
  • Prenatal diagnosis
  • Transvaginal sonography

ASJC Scopus subject areas

  • Genetics(clinical)
  • Obstetrics and Gynecology

Fingerprint

Dive into the research topics of 'Transvaginal sonography—detection of findings suggestive of fetal chromosomal anomalies in the first and early second trimesters'. Together they form a unique fingerprint.

Cite this