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Translation fidelity coevolves with longevity
Zhonghe Ke
, Pramit Mallik
, Adam B. Johnson
, Facundo Luna
,
Eviatar Nevo
, Zhengdong D. Zhang
, Vadim N. Gladyshev
, Andrei Seluanov
, Vera Gorbunova
Department of Evolutionary and Environmental Biology
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Keyphrases
Co-evolving
100%
Translation Quality
100%
Aging
80%
Protein Synthesis
60%
Codon
40%
Luciferase
40%
Maximum Lifespan
40%
Translation Errors
40%
Amino Acids
20%
Changes with Age
20%
Error Rate
20%
Amino Acid Residues
20%
Rodent Species
20%
Misincorporation
20%
Phylogenetic Correction
20%
Protein Synthesis Errors
20%
Luciferase Activity
20%
Reporter Construct
20%
Basal Rate
20%
Amino Acid Misincorporation
20%
Biochemistry, Genetics and Molecular Biology
Lifespan
100%
Protein Biosynthesis
100%
Amino Acids
75%
Luciferase
75%
Codon
50%
Immunology and Microbiology
Lifespan
100%
Protein Synthesis
100%
Amino Acid
75%
Codon
50%
Neuroscience
Protein Biosynthesis
100%
Amino Acid
75%
Luciferase
75%
Codon
50%