Transancestral fine-mapping of four type 2 diabetes susceptibility loci highlights potential causal regulatory mechanisms

Keyphrases

• African American 20%
• Allelic Effects 20%
• Association Signal 60%
• CDKAL1 20%
• Conditional Analysis 20%
• Cyclin-dependent Kinase Inhibitor 2A (CDKN2A) 20%
• Diabetes Susceptibility 100%
• Disease Susceptibility 20%
• Diverse Populations 20%
• East Asia 20%
• European South 20%
• Fine Mapping 100%
• Genetic Fine Mapping 20%
• Genome Annotation 20%
• High Density 20%
• Imputation Analysis 20%
• Insulin-like Growth Factor 2 mRNA-binding Protein 2 (IGF2BP2) 20%
• KCNQ1 20%
• Linkage Disequilibrium 20%
• Managing Differences 20%
• Mapping Data 20%
• Mexican Americans 20%
• Regulatory Elements 20%
• Regulatory Mechanism 100%
• South Asian 20%
• Susceptibility Loci 100%
• Type 2 Diabetes Mellitus (T2DM) 100%

Biochemistry, Genetics and Molecular Biology

• Cyclin Dependent Kinase Inhibitor 2A 100%