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The paradox of the insulin/IGF-1 signaling pathway in longevity
Marielisa Rincon
, Radhika Muzumdar
,
Gil Atzmon
, Nir Barzilai
Research output
:
Contribution to journal
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Review article
›
peer-review
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Keyphrases
Acquired Defects
12%
Age-related Illnesses
12%
Aging
25%
Central Nervous System
12%
Common Ancestor
12%
Disease-specific Mortality
12%
Diverse Functions
12%
Early Development
12%
Genetic Defects
12%
Growth Factors
12%
Hormonal System
12%
Human Longevity
12%
IGF Signaling
100%
IGF-1 Levels
12%
Increased Mortality
12%
Insulin
100%
Insulin Signaling
12%
Insulin Signaling Pathway
12%
Insulin-like
12%
Insulin-like Growth Factor 1 Receptor (IGF1R)
37%
Insulin-like Growth factor-1
25%
Invertebrates
12%
Metabolic Pathway
12%
Metabolism
12%
Nematodes
25%
Nervous System
12%
Paradoxical Results
12%
Prolonged Life
12%
Receptor Signaling
12%
Signaling Pathway
12%
Specific Receptor
12%
Biochemistry, Genetics and Molecular Biology
Animal Model
33%
Genetics
66%
Insulin Signaling
66%
Insulin-Like Growth Factor
33%
Insulin-Like Growth Factor 1 Receptor
100%
Lifespan
33%
Mammalia
66%
Metabolic Pathway
66%
Nematode
66%
Neuroscience
Cell Signaling
100%
Central Nervous System
33%
Insulin Signaling
33%
Insulin-Like Growth Factor 1 Receptor
100%
Metabolic Pathway
66%
Nervous System
33%
Receptor
33%
Somatomedin
33%
Agricultural and Biological Sciences
Central Nervous System
33%
Early Development
33%
Endocrine System
33%
Insulin-Like Growth Factor 1 Receptor
100%
Mammalia
66%
Nematode
66%
Nervous System
33%
Receptor
33%
Somatomedin
33%