The monetary incentive delay task breaks down reward processing into discrete stages for fMRI analysis. Here we look at anticipation of monetary gain and loss contrasted with neutral anticipation. We meta-analysed data from 15 original whole-brain group maps (n = 346) and report extensive areas of relative activation and deactivation throughout the whole brain. For both anticipation of gain and loss we report robust activation of the striatum, activation of key nodes of the putative salience network, including anterior cingulate and anterior insula, and more complex patterns of activation and deactivation in the central executive and default networks. On between-group comparison, we found significantly greater relative deactivation in the left inferior frontal gyrus associated with incentive valence. This meta-analysis provides a robust whole-brain map of a reward anticipation network in the healthy human brain.
Bibliographical noteFunding Information:
We would like to acknowledge the support of Joaquim Radua, Anton Albajes-Eizagirre, Christian Windischberger and Rupert Lanzenberger. Monetary Incentive Delay Task Analysis Consortium (MTAC) (arranged in alphabetical order): Abe, N, Barros-Loscertales, AR, Bayer, J, Beck, A, Bjork, J, Boecker, R, Bustamante, JC, Choi, JS, Delmonte, S, Dillon, D, Figee, M, Garavan, H, Hagele, C, Hermans, EJ, ICCAM Consortium, Ikeda, Y, Kappel, V, Kaufmann, C, Lamm, C, Lammertz, SE, Li, Y, Murphy, A, Nestor, L, Pecina, M, Pfabigan, D, Pizzagalli, D, Rademacher L, Admon, R, Sommer T, Stark, R, Suzuki, H, Van Amelsvoort, T, Van Hell, E, Vink M, Votinov, M, Wotruba, D.
Acknowledgements We would like to acknowledge the support of Joaquim Radua, Anton Albajes-Eizagirre, Christian Windischberger and Rupert Lanzenberger.
© 2018, The Author(s).
- Anticipation or reward
- Healthy adults
- Monetary incentive delay task
ASJC Scopus subject areas
- Neuropsychology and Physiological Psychology