The InterMed Approach to Sharable Computer-interpretable Guidelines: A Review

Mor Peleg, Aziz A. Boxwala, Samson Tu, Qing Zeng, Omolola Ogunyemi, Dongwen Wang, Vimla L. Patel, Robert A. Greenes, Edward H. Shortliffe

Research output: Contribution to journalArticlepeer-review


InterMed is a collaboration among research groups from Stanford, Harvard, and Columbia Universities. The primary goal of InterMed has been to develop a sharable language that could serve as a standard for modeling computer-interpretable guidelines (CIGs). This language, called GuideLine Interchange Format (GLIF), has been developed in a collaborative manner and in an open process that has welcomed input from the larger community. The goals and experiences of the InterMed project and lessons that the authors have learned may contribute to the work of other researchers who are developing medical knowledge-based tools. The lessons described include (1) a work process for multi-institutional research and development that considers different viewpoints, (2) an evolutionary lifecycle process for developing medical knowledge representation formats, (3) the role of cognitive methodology to evaluate and assist in the evolutionary development process, (4) development of an architecture and (5) design principles for sharable medical knowledge representation formats, and (6) a process for standardization of a CIG modeling language.

Original languageEnglish
Pages (from-to)1-10
Number of pages10
JournalJournal of the American Medical Informatics Association : JAMIA
Issue number1
StatePublished - 2004

Bibliographical note

Funding Information:
The authors thank Elmer V. Bernstam, Ronilda Lacson, Nachman Ash, and Peter Mork for their contribution to the development of the GLIF specification and guideline encoding. Supported in part by National Library of Medicine Grant LM06594 with collaborative support from the Department of the Army and the Agency for Healthcare Research and Quality.

ASJC Scopus subject areas

  • Health Informatics


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