The insula mediates access to awareness of visual stimuli presented synchronously to the heartbeat

Roy Salomon, Roberta Ronchi, Jonathan Dönz, Javier Bello-Ruiz, Bruno Herbelin, Remi Martet, Nathan Faivre, Karl Schaller, Olaf Blanke

Research output: Contribution to journalArticlepeer-review


The processing of interoceptive signals in the insular cortex is thought to underlie self-awareness. However, the influence of interoception on visual awareness and the role of the insular cortex in this process remain unclear. Here, we show in a series of experiments that the relative timing of visual stimuli with respect to the heartbeat modulates visual awareness.Weused two masking techniques and show that conscious access for visual stimuli synchronous to participants’ heartbeat is suppressed compared with the same stimuli presented asynchronously to their heartbeat. Two independent brain imaging experiments using high-resolution fMRI revealed that the insular cortex was sensitive to both visible and invisible cardio-visual stimulation, showing reduced activation for visual stimuli presented synchronously to the heartbeat. Our results show that interoceptive insular processing affects visual awareness, demonstrating the role of the insula in integrating interoceptive and exteroceptive signals and in the processing of conscious signals beyond self-awareness.

Original languageEnglish
Pages (from-to)5115-5127
Number of pages13
JournalJournal of Neuroscience
Issue number18
StatePublished - 4 May 2016
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2016 the authors.


  • Continuous flash suppression
  • High-resolution fMRI
  • Insula
  • Interoception
  • Visual awareness

ASJC Scopus subject areas

  • General Neuroscience


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