Abstract
The evolutionary significance of genetic diversity of proteins in nature remains controversial despite the numerous protein studies conducted electrophoretically during the last two decades. Ironically, the discovery of extensive protein polymorphisms in nature (reviewed by Lewontin, 1974; Powell, 1975; Selander, 1976; Nevo 1978, 1983b; Hamrick et al., 1979; Nelson and Hedgecock, 1980), did not resolve the disagreement between the die ho torn ou s explanatory models of selection (e.g., Ayala, 1977; Milkman, 1978; Clarke, 1979; Wills, 1981) versus neutrality (Kimura, 1968; Kimura and Chta, 1971; Nei, 1975; and modifications in Kimura, 1979atb). The more general problem of the relative importance of the evolutionary forces interacting in genetic population differentiation at the molecular levels of proteins and DNA, i.e., mutation, migration, natural selection and genetic drift, remains now as enigmatic as ever.
Original language | English |
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Title of host publication | Evolutionary Dynamics of Genetic Diversity |
Subtitle of host publication | Proceedings of a Symposium held in Manchester, England, March 29–30, 1983 |
Editors | G. S. Mani |
Place of Publication | Berlin |
Publisher | Springer Heidelberg |
Pages | 13-213 |
Number of pages | 201 |
ISBN (Electronic) | 978-3-642-51588-0 |
ISBN (Print) | 978-3-540-12903-5 |
DOIs | |
State | Published - 1 Mar 1984 |