The effect of social selection on the population dynamics of Huntington's disease

SHOZO YOKOYAMA, ALAN TEMPLETON

Research output: Contribution to journalArticlepeer-review

Abstract

Wallace (1976) postulated the importance of social selection on the frequency of Huntington's disease. This effect of social selection was studied with respect to the population dynamics of Huntington's disease genes. It is shown that social selection operates mainly through heterozygotes. Existing data indicate that the frequency of Huntington's disease in the population is determined by its social effects.

Original languageEnglish
Pages (from-to)413-418
Number of pages6
JournalAnnals of Human Genetics
Volume43
Issue number4
DOIs
StatePublished - May 1980
Externally publishedYes

ASJC Scopus subject areas

  • Genetics(clinical)
  • Genetics

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