The Dynamics Of The Ab Neuron: Thirty-seventh Annual Meeting February 14–18, 1993 Washington Convention Center Washington, D.C: Monday Symposia and Posters, Part IV

John Guckenheimer, Shay Gueron, Ronald M. Harris-Warrick

Research output: Contribution to journalConference articlepeer-review

Abstract

The Anterior Burster (AB) neuron of the lobster stomatogastric ganglion displays varied behavior when subjected to application of neu- romodulators and toxins. We introduce a new, channel based model for this neuron and investigate the response of this model to changes of its parameters. An efficient computational environment aids in the determination of the bifurcations in the model, separating regions of the parameter space with different types of behavior. The model pre- dictions compare well with a limited set of experimental data.
Different two dimensional slices of the parameter space are mapped. They correspond to the application of specific-channel blockers to an experimental preparation. These mapped regions are used to predict the effects of Dopamine on the AB cell ion channels, and to suggest some experiments to support these conjectures.
Original languageEnglish
Pages (from-to)A98
Number of pages1
JournalBiophysical Journal
Volume64
Issue number2
DOIs
StatePublished - Feb 1993
Externally publishedYes

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