The Consolidation and Transformation of Memory

Yadin Dudai, Avi Karni, Jan Born

Research output: Contribution to journalReview articlepeer-review


Memory consolidation refers to the transformation over time of experience-dependent internal representations and their neurobiological underpinnings. The process is assumed to be embodied in synaptic and cellular modifications at brain circuits in which the memory is initially encoded and to proceed by recurrent reactivations, both during wakefulness and during sleep, culminating in the distribution of information to additional locales and integration of new information into existing knowledge. We present snapshots of our current knowledge and gaps in knowledge concerning the progress of consolidation over time and the cognitive architecture that supports it and shapes our long-term memories.

Original languageEnglish
Article number12818
Pages (from-to)20-32
Number of pages13
Issue number1
StatePublished - 7 Oct 2015

Bibliographical note

Publisher Copyright:
© 2015 Elsevier Inc.

ASJC Scopus subject areas

  • General Neuroscience


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