Tandem protein kinases emerge as new regulators of plant immunity

Valentyna Klymiuk, Gitta Coaker, Tzion Fahima, Curtis J. Pozniak

Research output: Contribution to journalReview articlepeer-review

Abstract

Plant–pathogen interactions result in disease development in a susceptible host. Plants actively resist pathogens via a complex immune system comprising both surface-localized receptors that sense the extracellular space as well as intracellular receptors recognizing pathogen effectors. To date, the majority of cloned resistance genes encode intracellular nucleotide-binding leucine-rich repeat receptor proteins. Recent discoveries have revealed tandem kinase proteins (TKPs) as another important family of intracellular proteins involved in plant immune responses. Five TKP genes—barley Rpg1 and wheat WTK1 (Yr15), WTK2 (Sr60), WTK3 (Pm24), and WTK4—protect against devastating fungal diseases. Moreover, a large diversity and numerous putative TKPs exist across the plant kingdom. This review explores our current knowledge of TKPs and serves as a basis for future studies that aim to develop and exploit a deeper understanding of innate plant immunity receptor proteins.

Original languageEnglish
JournalMolecular Plant-Microbe Interactions
Volume34
Issue number10
DOIs
StatePublished - Oct 2021

Bibliographical note

Funding Information:
Funding: Supported was provided to G. Coaker and T. Fahima by the United States National Science Foundation (1937855), the United States Department of Agriculture (2020-67013-32577), and the United States-Israel Binational Science Foundation (2019654).

Publisher Copyright:
Copyright © 2021 The Author(s).

Keywords

  • Fungus–plant interactions
  • Intracellular perception proteins
  • Plant defense response system
  • Plant responses to pathogens
  • Plant–pathogen interactions
  • Pm24
  • Resistance gene
  • Rpg1
  • Sr60
  • WTK4
  • Wheat tandem kinase (WTK)
  • Yr15

ASJC Scopus subject areas

  • Physiology
  • Agronomy and Crop Science

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