Tadalafil and acetazolamide versus acetazolamide for the prevention of severe high-altitude illness

Eyal Leshem; Yehezkel Caine; Elliot Rosenberg; Yoram Maaravi; Hagai Hermesh; Eli Schwartz

doi:10.1111/j.1708-8305.2012.00636.x

Tadalafil and acetazolamide versus acetazolamide for the prevention of severe high-altitude illness

Eyal Leshem, Yehezkel Caine, Elliot Rosenberg, Yoram Maaravi, Hagai Hermesh, Eli Schwartz

Research output: Contribution to journal › Article › peer-review

Abstract

We report an open-label study comparing tadalafil and acetazolamide (n = 24) versus acetazolamide (n = 27) for prevention of high-altitude illness (HAI) at Mt. Kilimanjaro. Tadalafil group had lower rates of severe HAI compared with controls (4% vs 26%, p = 0.03), mostly because of decreased high-altitude pulmonary edema rates (4% vs 22%, p = 0.06).

Original language	English
Pages (from-to)	308-310
Number of pages	3
Journal	Journal of Travel Medicine
Volume	19
Issue number	5
DOIs	https://doi.org/10.1111/j.1708-8305.2012.00636.x
State	Published - Sep 2012
Externally published	Yes

ASJC Scopus subject areas

Public Health, Environmental and Occupational Health
Infectious Diseases

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10.1111/j.1708-8305.2012.00636.x

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AU - Hermesh, Hagai

AU - Schwartz, Eli

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Tadalafil and acetazolamide versus acetazolamide for the prevention of severe high-altitude illness

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ASJC Scopus subject areas

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