Study of the properties of exogenous recombinant human heat shock protein HSP70 using a rodent sepsis model

V. F. Ostrov; M. B. Evgen'Ev; A. N. Murashev

doi:10.1134/S1068162011030125

Study of the properties of exogenous recombinant human heat shock protein HSP70 using a rodent sepsis model

V. F. Ostrov
, M. B. Evgen'Ev
, A. N. Murashev

Research output: Contribution to journal › Article › peer-review

Abstract

The protective effects of the exogenous recombinant human heat shock protein with a molecular mass of 70 kDa (rhHSP70) were demonstrated on blood laboratory indices following exogenous injection into Sprague-Dawley rats with induced gram-positive sepsis. Acute toxicity of the protein was studied on CD-1 rats.

Original language	English
Pages (from-to)	322-325
Number of pages	4
Journal	Russian Journal of Bioorganic Chemistry
Volume	37
Issue number	3
DOIs	https://doi.org/10.1134/S1068162011030125
State	Published - May 2011
Externally published	Yes

Keywords

acute toxicity
blood biochemical indices
heat shock proteins
lipoteichoic acid
multiorgan dysfunction syndrome
sepsis

ASJC Scopus subject areas

Biochemistry
Organic Chemistry

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10.1134/S1068162011030125

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title = "Study of the properties of exogenous recombinant human heat shock protein HSP70 using a rodent sepsis model",

abstract = "The protective effects of the exogenous recombinant human heat shock protein with a molecular mass of 70 kDa (rhHSP70) were demonstrated on blood laboratory indices following exogenous injection into Sprague-Dawley rats with induced gram-positive sepsis. Acute toxicity of the protein was studied on CD-1 rats.",

keywords = "acute toxicity, blood biochemical indices, heat shock proteins, lipoteichoic acid, multiorgan dysfunction syndrome, sepsis",

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year = "2011",

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AU - Evgen'Ev, M. B.

AU - Murashev, A. N.

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AB - The protective effects of the exogenous recombinant human heat shock protein with a molecular mass of 70 kDa (rhHSP70) were demonstrated on blood laboratory indices following exogenous injection into Sprague-Dawley rats with induced gram-positive sepsis. Acute toxicity of the protein was studied on CD-1 rats.

KW - acute toxicity

KW - blood biochemical indices

KW - heat shock proteins

KW - lipoteichoic acid

KW - multiorgan dysfunction syndrome

KW - sepsis

UR - https://www.scopus.com/pages/publications/79960148951

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M3 - Article

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ER -

Study of the properties of exogenous recombinant human heat shock protein HSP70 using a rodent sepsis model

Abstract

Keywords

ASJC Scopus subject areas

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