Study of the properties of exogenous recombinant human heat shock protein HSP70 using a rodent sepsis model

V. F. Ostrov; M. B. Evgen'Ev; A. N. Murashev

doi:10.1134/S1068162011030125

Study of the properties of exogenous recombinant human heat shock protein HSP70 using a rodent sepsis model

V. F. Ostrov, M. B. Evgen'Ev, A. N. Murashev

Research output: Contribution to journal › Article › peer-review

Abstract

The protective effects of the exogenous recombinant human heat shock protein with a molecular mass of 70 kDa (rhHSP70) were demonstrated on blood laboratory indices following exogenous injection into Sprague-Dawley rats with induced gram-positive sepsis. Acute toxicity of the protein was studied on CD-1 rats.

Original language	English
Pages (from-to)	322-325
Number of pages	4
Journal	Russian Journal of Bioorganic Chemistry
Volume	37
Issue number	3
DOIs	https://doi.org/10.1134/S1068162011030125
State	Published - May 2011
Externally published	Yes

Keywords

acute toxicity
blood biochemical indices
heat shock proteins
lipoteichoic acid
multiorgan dysfunction syndrome
sepsis

ASJC Scopus subject areas

Biochemistry
Organic Chemistry

Access to Document

10.1134/S1068162011030125

Cite this

@article{d07b96c38e9642ab8d4b67cc548764fb,

title = "Study of the properties of exogenous recombinant human heat shock protein HSP70 using a rodent sepsis model",

abstract = "The protective effects of the exogenous recombinant human heat shock protein with a molecular mass of 70 kDa (rhHSP70) were demonstrated on blood laboratory indices following exogenous injection into Sprague-Dawley rats with induced gram-positive sepsis. Acute toxicity of the protein was studied on CD-1 rats.",

keywords = "acute toxicity, blood biochemical indices, heat shock proteins, lipoteichoic acid, multiorgan dysfunction syndrome, sepsis",

author = "Ostrov, {V. F.} and Evgen'Ev, {M. B.} and Murashev, {A. N.}",

year = "2011",

month = may,

doi = "10.1134/S1068162011030125",

language = "English",

volume = "37",

pages = "322--325",

journal = "Russian Journal of Bioorganic Chemistry",

issn = "1068-1620",

publisher = "Pleiades Publishing",

number = "3",

}

TY - JOUR

T1 - Study of the properties of exogenous recombinant human heat shock protein HSP70 using a rodent sepsis model

AU - Ostrov, V. F.

AU - Evgen'Ev, M. B.

AU - Murashev, A. N.

PY - 2011/5

Y1 - 2011/5

N2 - The protective effects of the exogenous recombinant human heat shock protein with a molecular mass of 70 kDa (rhHSP70) were demonstrated on blood laboratory indices following exogenous injection into Sprague-Dawley rats with induced gram-positive sepsis. Acute toxicity of the protein was studied on CD-1 rats.

AB - The protective effects of the exogenous recombinant human heat shock protein with a molecular mass of 70 kDa (rhHSP70) were demonstrated on blood laboratory indices following exogenous injection into Sprague-Dawley rats with induced gram-positive sepsis. Acute toxicity of the protein was studied on CD-1 rats.

KW - acute toxicity

KW - blood biochemical indices

KW - heat shock proteins

KW - lipoteichoic acid

KW - multiorgan dysfunction syndrome

KW - sepsis

UR - http://www.scopus.com/inward/record.url?scp=79960148951&partnerID=8YFLogxK

U2 - 10.1134/S1068162011030125

DO - 10.1134/S1068162011030125

M3 - Article

AN - SCOPUS:79960148951

SN - 1068-1620

VL - 37

SP - 322

EP - 325

JO - Russian Journal of Bioorganic Chemistry

JF - Russian Journal of Bioorganic Chemistry

IS - 3

ER -

Study of the properties of exogenous recombinant human heat shock protein HSP70 using a rodent sepsis model

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this