Stereoselective synthesis of metalated cyclobutyl derivatives

Einav Tsoglin, Helena Chechik, Guy Karseboom, Nicka Chinkov, Amnon Stanger, Ilan Marek

Research output: Contribution to journalArticlepeer-review


Treatment of Z-vinyl carbamates with dicyclopentadienyl(diethyl)zirconium [Et2ZrCp2] leads to cyclobutyl-zirconocene derivatives in good yields and as a unique diastereoisomer. The reaction proceeds through a carbometalative ring-expansion followed by an intramolecular migratory insertion.

Original languageEnglish
Pages (from-to)1005-1008
Number of pages4
JournalAdvanced Synthesis and Catalysis
Issue number7-8
StatePublished - May 2009
Externally publishedYes


  • Carbometalation
  • Cyclobutanes
  • Enol car-bamates
  • Ring expansion
  • Zirconocenes

ASJC Scopus subject areas

  • Catalysis
  • Organic Chemistry


Dive into the research topics of 'Stereoselective synthesis of metalated cyclobutyl derivatives'. Together they form a unique fingerprint.

Cite this