Small is mighty: EmrE, a multidrug transporter as an experimental paradigm

Shimon Schuldiner; Dorit Granot; Sonia Steiner Mordoch; Shira Ninio; Dvir Rotem; Michael Soskin; Christopher G. Tate; Hagit Yerushalmi

doi:10.1152/physiologyonline.2001.16.3.130

Small is mighty: EmrE, a multidrug transporter as an experimental paradigm

Shimon Schuldiner
, Dorit Granot
, Sonia Steiner Mordoch
, Shira Ninio
, Dvir Rotem
, Michael Soskin
, Christopher G. Tate
, Hagit Yerushalmi

Research output: Contribution to journal › Article › peer-review

Abstract

EmrE is a multidrug transporter from Escherichia coli that functions as a homooligomer and is unique in its small size. In each monomer there are four tightly packed transmembrane segments and one membrane-embedded charged residue. This residue provides the basis for the coupling mechanism as part of a binding site "time shared" by substrates and protons.

Original language	English
Pages (from-to)	130-134
Number of pages	5
Journal	News in Physiological Sciences
Volume	16
Issue number	3
DOIs	https://doi.org/10.1152/physiologyonline.2001.16.3.130
State	Published - Jun 2001
Externally published	Yes

ASJC Scopus subject areas

Physiology

Access to Document

10.1152/physiologyonline.2001.16.3.130

Cite this

@article{72f651de48194a839c90e640c0f2ddac,

title = "Small is mighty: EmrE, a multidrug transporter as an experimental paradigm",

abstract = "EmrE is a multidrug transporter from Escherichia coli that functions as a homooligomer and is unique in its small size. In each monomer there are four tightly packed transmembrane segments and one membrane-embedded charged residue. This residue provides the basis for the coupling mechanism as part of a binding site {"}time shared{"} by substrates and protons.",

author = "Shimon Schuldiner and Dorit Granot and Mordoch, \{Sonia Steiner\} and Shira Ninio and Dvir Rotem and Michael Soskin and Tate, \{Christopher G.\} and Hagit Yerushalmi",

year = "2001",

month = jun,

doi = "10.1152/physiologyonline.2001.16.3.130",

language = "English",

volume = "16",

pages = "130--134",

journal = "News in Physiological Sciences",

issn = "0886-1714",

publisher = "American Physiological Society",

number = "3",

}

TY - JOUR

T1 - Small is mighty

T2 - EmrE, a multidrug transporter as an experimental paradigm

AU - Schuldiner, Shimon

AU - Granot, Dorit

AU - Mordoch, Sonia Steiner

AU - Ninio, Shira

AU - Rotem, Dvir

AU - Soskin, Michael

AU - Tate, Christopher G.

AU - Yerushalmi, Hagit

PY - 2001/6

Y1 - 2001/6

N2 - EmrE is a multidrug transporter from Escherichia coli that functions as a homooligomer and is unique in its small size. In each monomer there are four tightly packed transmembrane segments and one membrane-embedded charged residue. This residue provides the basis for the coupling mechanism as part of a binding site "time shared" by substrates and protons.

AB - EmrE is a multidrug transporter from Escherichia coli that functions as a homooligomer and is unique in its small size. In each monomer there are four tightly packed transmembrane segments and one membrane-embedded charged residue. This residue provides the basis for the coupling mechanism as part of a binding site "time shared" by substrates and protons.

UR - https://www.scopus.com/pages/publications/0035354575

U2 - 10.1152/physiologyonline.2001.16.3.130

DO - 10.1152/physiologyonline.2001.16.3.130

M3 - Article

C2 - 11443233

AN - SCOPUS:0035354575

SN - 0886-1714

VL - 16

SP - 130

EP - 134

JO - News in Physiological Sciences

JF - News in Physiological Sciences

IS - 3

ER -

Small is mighty: EmrE, a multidrug transporter as an experimental paradigm

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this