Simulations in genome mapping

David Mester, Yefim Ronin, Zeev Frenkel, Dina Mitnov, Abraham Korol

Research output: Contribution to conferencePaperpeer-review

Abstract

Genome mapping is a major part of genome projects and precondition for most genomic applications. Any organism with economical or ecological importance is (or will be) a target for genome mapping. The aim of this workshop is to demonstrate simulation and optimization methods employed in our software packages for genome mapping, including construction of genetic maps, mapping quantitative trait loci (QTL) and building physical maps. The presented paper describes the process of simulations in these packages in three aspects: (i) for generation artificial datasets with intended properties in order to compare different analytical approaches, (ii) for analysis of solution quality, and (iii) as a central component in Evolutionary Optimization algorithms that mimic natural population - biology processes.

Original languageEnglish
Pages78-83
Number of pages6
StatePublished - 2012
Event26th European Simulation and Modelling Conference, ESM 2012 - Essen, Germany
Duration: 22 Oct 201224 Oct 2012

Conference

Conference26th European Simulation and Modelling Conference, ESM 2012
Country/TerritoryGermany
CityEssen
Period22/10/1224/10/12

Keywords

  • Multilocus genetic mapping
  • Physical mapping
  • QTL-mapping
  • Simulations

ASJC Scopus subject areas

  • Modeling and Simulation

Fingerprint

Dive into the research topics of 'Simulations in genome mapping'. Together they form a unique fingerprint.

Cite this