Silica, silicosis, and lung cancer

Alon Peretz, Harvey Checkoway, Joel D. Kaufman, Israel Trajber, Yehuda Lerman

Research output: Contribution to journalReview articlepeer-review

Abstract

Evidence that crystalline silica is associated with an increased rate of lung cancer led the International Agency for Research on Cancer to conclude in 1997 that crystalline silica is a known human carcinogen. In Israel too, crystalline silica is considered as such. The decision raised a debate in the scientific arena, and a few scientists have questioned the basis upon which causality was determined. We review the literature regarding the level of evidence of crystalline silica carcinogenicity.

Original languageEnglish
Pages (from-to)114-118
Number of pages5
JournalIsrael Medical Association Journal
Volume8
Issue number2
StatePublished - Feb 2006
Externally publishedYes

Keywords

  • Causality
  • IARC classification
  • Lung cancer
  • Silica
  • Silicosis

ASJC Scopus subject areas

  • Medicine (all)

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