Safety of traditional Arab herbal medicine

Bashar Saad, Hassan Azaizeh, Ghassan Abu-Hijleh, Omar Said

Research output: Contribution to journalReview articlepeer-review

Abstract

Herbal remedies are widely used for the treatment and prevention of various diseases and often contain highly active pharmacological compounds. Many medicinal herbs and pharmaceutical drugs are therapeutic at one dose and toxic at another. Toxicity related to traditional medicines is becoming more widely recognized as these remedies become popular in the Mediterranean region as well as worldwide. Most reports concerning the toxic effects of herbal medicines are associated with hepatotoxicity although reports of other toxic effects including kidney, nervous system, blood, cardiovascular and dermatologic effects, mutagenicity and carcinogenicity have also been published in the medical literature. This article presents a systematic review on safety of traditional Arab medicine and the contribution of Arab scholars to toxicology. Use of modern cell biological, biochemical, in vitro and in vivo techniques for the evaluation of medicinal plants safety is also discussed.

Original languageEnglish
Pages (from-to)433-439
Number of pages7
JournalEvidence-based Complementary and Alternative Medicine
Volume3
Issue number4
DOIs
StatePublished - Dec 2006

Keywords

  • Arab herbal medicine
  • Complementary and alternative medicine (CAM)
  • In vitro
  • In vivo
  • Toxicity tests

ASJC Scopus subject areas

  • Complementary and alternative medicine

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