Rare coding variants in 35 genes associate with circulating lipid levels—A multi-ancestry analysis of 170,000 exomes

Keyphrases

• Gene Association 100%
• Genome-wide Association Study 100%
• Exome 100%
• Lipid Levels 100%
• Ancestry Analysis 100%
• Multi-ancestry 100%
• Rare Coding Variants 100%
• Circulating Lipids 100%
• Single nucleotide Polymorphism 66%
• Array-based 66%
• Blood Lipid Profile 66%
• Gene Sequencing 33%
• Complex Traits 33%
• Associated Genes 33%
• Population-based Sample 33%
• Functional Genes 33%
• Low-density Lipoprotein Cholesterol (LDL-C) 33%
• East Asia 33%
• Drug Target 33%
• Minor Allele Frequency 33%
• Sequencing Studies 33%
• Therapeutic Implications 33%
• Causal Genes 33%
• Hispanic or Latino 33%
• Samoan 33%
• Drug Target Genes 33%
• PLIN1 33%
• EVI5 33%
• South Asian 33%
• Association Testing 33%
• SH2B3 33%

Biochemistry, Genetics and Molecular Biology

• Lipid 100%
• Exome 100%
• Genome-Wide Association Study 100%
• Lipid Level 100%
• Single-Nucleotide Polymorphism 66%
• Blood Lipids 66%
• Gene Sequence 33%
• Minor Allele Frequency 33%
• SH2B3 33%
• Low-Density Lipoprotein 33%