Prospective associations between cannabis use, abuse, and dependence and panic attacks and disorder

Michael J. Zvolensky, Peter Lewinsohn, Amit Bernstein, Norman B. Schmidt, Julia D. Buckner, John Seeley, Marcel O. Bonn-Miller

Research output: Contribution to journalArticlepeer-review

Abstract

The present study prospectively evaluated cannabis use, abuse, and dependence in relation to the development of panic attacks and panic disorder. Participants at the start of the study were adolescents (n = 1709) with a mean age of 16.6 years (SD = 1.2; time 1) and were re-assessed 1 year later (time 2) and then again as young adults (time 3; mean age = 24.2 years, SD = 0.6). Results indicated that cannabis use and dependence were significantly prospectively associated with an increased odds for the development of panic attacks and panic disorder. However, cannabis was not incrementally associated with the development of panic after controlling for daily cigarette smoking. The theoretical and clinical implications of these findings are discussed.

Original languageEnglish
Pages (from-to)1017-1023
Number of pages7
JournalJournal of Psychiatric Research
Volume42
Issue number12
DOIs
StatePublished - Oct 2008
Externally publishedYes

Bibliographical note

Funding Information:
This paper was supported by National Institute on Drug Abuse research grants (1 R01 DA018734-01A1, R03 DA16307-01, and 1 R21 DA016227-01) awarded to Dr. Zvolensky. Dr. Bernstein acknowledges that this work was supported in part by VA Office of Academic Affairs and Health Services Research and Development Service Research funds.

Funding Information:
This paper was supported by National Institute on Drug Abuse research grants (1 R01 DA018734-01A1, R03 DA16307-01, and 1 R21 DA016227-01) awarded to Dr. Zvolensky. Dr. Bernstein acknowledges that this work was supported in part by VA Office of Academic Affairs and Health Services Research and Development Service Research funds.

Keywords

  • Cannabis
  • Drug dependence
  • Marijuana
  • Panic attacks
  • Panic disorder
  • Smoking

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry

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