Professor Shu-Ting Chang, cancer mycotherapy and Le Chatelier principle

Ivan V. Zmitrovich, Stanislav P. Arefyev, Margarita A. Bondartseva, Solomon P. Wasser

Research output: Contribution to journalArticlepeer-review


In the jubilee paper devoted to Professor Shu-Ting Chang, we aimed to outline the applicability of the Le Chatelier principle to various fields, especially to cancer biology and immunotherapy of malignant neoplasms. Cancer progression has been shown to be associated with a response to cell stress and survival agents. It was proclaimed that cancer immunotherapy, using fungal metabolites, should be carried out as a mode of compensation for imbalances that arise during the basic treatment. The challenges of immunotherapy in recent years have also received mention.

Original languageEnglish
Pages (from-to)835-844
Number of pages10
JournalInternational Journal of Medicinal Mushrooms
Issue number9
StatePublished - 2020

Bibliographical note

Funding Information:
The work of M.A. Bondartseva and I.V. Zmitrovich was carried out in the framework of the State Task of the V.L. Komarov Botanical Institute of the Russian Academy of Sciences (N АААА-А19-119080990059-1). The work by S.P. Arefyev was carried out in the framework of State Task of the Institute of Problems of Development of the North – subdivision of Federal Research Center Tyumen Scientific Center of Siberian Branch of the Russian Academy of Sciences (N АААА-А17-117050400146-5).

Publisher Copyright:
© 2020 by Begell House, Inc.


  • Cancer biology
  • Cell survival
  • Glycobiology
  • Immunotherapy
  • Le Chatelier principle
  • Medicinal mush-rooms
  • Target cancer therapy

ASJC Scopus subject areas

  • Applied Microbiology and Biotechnology
  • Pharmacology
  • Drug Discovery


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