Abstract
The frequency of pregnancy-associated breast cancer, a rare but serious occurrence, may increase in light of the secular trends for lower parity in general and for older age at first full-term delivery in particular. Data on PABC in individuals who are at high risk for breast cancer are limited. A computerized search of Pubmed showed that the reported incidence of PABC is 1:3000 pregnancies; it is often diagnosed at an advanced stage and its prognosis is inferior compared to non-PABC. Carriers of mutations in the genes BRCA1/2 may present a specific high risk group for PABC especially at younger ages. Women treated with fertility treatment drugs may be at a higher risk for PABC as well.
Original language | English |
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Pages (from-to) | 722-727 |
Number of pages | 6 |
Journal | Israel Medical Association Journal |
Volume | 10 |
Issue number | 10 |
State | Published - Oct 2008 |
Keywords
- BRCA carriers
- Breast cancer
- Literature review
- Pregnancy-associated breast cancer
ASJC Scopus subject areas
- General Medicine