Pregnancy-associated breast cancer

Lital Keinan-Boker, Liat Lerner-Geva, Bella Kaufman, Dror Meirow

Research output: Contribution to journalReview articlepeer-review


The frequency of pregnancy-associated breast cancer, a rare but serious occurrence, may increase in light of the secular trends for lower parity in general and for older age at first full-term delivery in particular. Data on PABC in individuals who are at high risk for breast cancer are limited. A computerized search of Pubmed showed that the reported incidence of PABC is 1:3000 pregnancies; it is often diagnosed at an advanced stage and its prognosis is inferior compared to non-PABC. Carriers of mutations in the genes BRCA1/2 may present a specific high risk group for PABC especially at younger ages. Women treated with fertility treatment drugs may be at a higher risk for PABC as well.

Original languageEnglish
Pages (from-to)722-727
Number of pages6
JournalIsrael Medical Association Journal
Issue number10
StatePublished - Oct 2008


  • BRCA carriers
  • Breast cancer
  • Literature review
  • Pregnancy-associated breast cancer

ASJC Scopus subject areas

  • General Medicine


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