Preferred positions of aa and tt dinucleotides in aligned nucleosomal dna sequences

I. Ioshikhes; A. Bolshoy; E. N. Trifonov

doi:10.1080/07391102.1992.10507982

Preferred positions of aa and tt dinucleotides in aligned nucleosomal dna sequences

I. Ioshikhes, A. Bolshoy, E. N. Trifonov

Research output: Contribution to journal › Article › peer-review

Abstract

Multiple alignment of 118 nucleosomal DNA sequences by maximizing simultaneously match of AA dinucleotides and match of TT dinucleotides results in a pattern of the dinucleotide distributions which is characteristic of the nucleosomal DNA sequences. The AA dinucleotides are found to be distributed symmetrically relative to the TT dinucleotide distribution, around the middle point of the nucleosomal DNA sequence. The distances between major peaks of the distributions are multiples of about 10.4 bases. The peaks of the TT distribution are shifted by 6 bases downstream from the peaks of the AA distribution.

Original language	English
Pages (from-to)	1111-1118
Number of pages	8
Journal	Journal of Biomolecular Structure and Dynamics
Volume	9
Issue number	6
DOIs	https://doi.org/10.1080/07391102.1992.10507982
State	Published - Jun 1992
Externally published	Yes

Bibliographical note

Funding Information:
This work has been supported by Ministry of Absorbtion and by Ministry of Science and Technology. Authors appreciate discussions with Dr. L. Garber.

ASJC Scopus subject areas

Structural Biology
Molecular Biology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1080/07391102.1992.10507982

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abstract = "Multiple alignment of 118 nucleosomal DNA sequences by maximizing simultaneously match of AA dinucleotides and match of TT dinucleotides results in a pattern of the dinucleotide distributions which is characteristic of the nucleosomal DNA sequences. The AA dinucleotides are found to be distributed symmetrically relative to the TT dinucleotide distribution, around the middle point of the nucleosomal DNA sequence. The distances between major peaks of the distributions are multiples of about 10.4 bases. The peaks of the TT distribution are shifted by 6 bases downstream from the peaks of the AA distribution.",

author = "I. Ioshikhes and A. Bolshoy and Trifonov, {E. N.}",

note = "Funding Information: This work has been supported by Ministry of Absorbtion and by Ministry of Science and Technology. Authors appreciate discussions with Dr. L. Garber.",

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doi = "10.1080/07391102.1992.10507982",

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T1 - Preferred positions of aa and tt dinucleotides in aligned nucleosomal dna sequences

AU - Ioshikhes, I.

AU - Bolshoy, A.

AU - Trifonov, E. N.

N1 - Funding Information: This work has been supported by Ministry of Absorbtion and by Ministry of Science and Technology. Authors appreciate discussions with Dr. L. Garber.

PY - 1992/6

Y1 - 1992/6

N2 - Multiple alignment of 118 nucleosomal DNA sequences by maximizing simultaneously match of AA dinucleotides and match of TT dinucleotides results in a pattern of the dinucleotide distributions which is characteristic of the nucleosomal DNA sequences. The AA dinucleotides are found to be distributed symmetrically relative to the TT dinucleotide distribution, around the middle point of the nucleosomal DNA sequence. The distances between major peaks of the distributions are multiples of about 10.4 bases. The peaks of the TT distribution are shifted by 6 bases downstream from the peaks of the AA distribution.

AB - Multiple alignment of 118 nucleosomal DNA sequences by maximizing simultaneously match of AA dinucleotides and match of TT dinucleotides results in a pattern of the dinucleotide distributions which is characteristic of the nucleosomal DNA sequences. The AA dinucleotides are found to be distributed symmetrically relative to the TT dinucleotide distribution, around the middle point of the nucleosomal DNA sequence. The distances between major peaks of the distributions are multiples of about 10.4 bases. The peaks of the TT distribution are shifted by 6 bases downstream from the peaks of the AA distribution.

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DO - 10.1080/07391102.1992.10507982

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JO - Journal of Biomolecular Structure and Dynamics

JF - Journal of Biomolecular Structure and Dynamics

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ER -

Preferred positions of aa and tt dinucleotides in aligned nucleosomal dna sequences

Abstract

Bibliographical note

ASJC Scopus subject areas

UN SDGs

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