Physical aspects of a spatially fractionated radiotherapy technique for large soft tissue sarcomas

Egor Borzov; Raquel Bar-Deroma; Myroslav Lutsyk

doi:10.1016/j.phro.2022.04.010

Physical aspects of a spatially fractionated radiotherapy technique for large soft tissue sarcomas

Egor Borzov, Raquel Bar-Deroma, Myroslav Lutsyk

Research output: Contribution to journal › Article › peer-review

Abstract

This work demonstrates the safety and feasibility of Lattice Radiotherapy (LRT) for large soft tissue sarcoma in neoadjuvant radiotherapy. The treatment consisted of two courses: the LRT course with a single fraction of 20 Gy delivered to high dose nuclei (HDN) regions and the conventional course with 25 fractions of 2 Gy delivered to the planning target volume. HDN shaped as cylinders with a 1 cm diameter and 1 cm height were placed within the gross tumour volume. The number of HDNs and their position were determined based on tumor size and proximity to organs at risk. Three patients were irradiated using the LRT technique.

Original language	English
Pages (from-to)	63-66
Number of pages	4
Journal	Physics and Imaging in Radiation Oncology
Volume	22
DOIs	https://doi.org/10.1016/j.phro.2022.04.010
State	Published - Apr 2022
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2022 The Author(s)

Keywords

GRID
LRT
SFRT
Soft tissue sarcoma

ASJC Scopus subject areas

Radiation
Oncology
Radiology Nuclear Medicine and imaging

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.phro.2022.04.010

Cite this

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title = "Physical aspects of a spatially fractionated radiotherapy technique for large soft tissue sarcomas",

abstract = "This work demonstrates the safety and feasibility of Lattice Radiotherapy (LRT) for large soft tissue sarcoma in neoadjuvant radiotherapy. The treatment consisted of two courses: the LRT course with a single fraction of 20 Gy delivered to high dose nuclei (HDN) regions and the conventional course with 25 fractions of 2 Gy delivered to the planning target volume. HDN shaped as cylinders with a 1 cm diameter and 1 cm height were placed within the gross tumour volume. The number of HDNs and their position were determined based on tumor size and proximity to organs at risk. Three patients were irradiated using the LRT technique.",

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doi = "10.1016/j.phro.2022.04.010",

language = "English",

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T1 - Physical aspects of a spatially fractionated radiotherapy technique for large soft tissue sarcomas

AU - Borzov, Egor

AU - Bar-Deroma, Raquel

AU - Lutsyk, Myroslav

PY - 2022/4

Y1 - 2022/4

N2 - This work demonstrates the safety and feasibility of Lattice Radiotherapy (LRT) for large soft tissue sarcoma in neoadjuvant radiotherapy. The treatment consisted of two courses: the LRT course with a single fraction of 20 Gy delivered to high dose nuclei (HDN) regions and the conventional course with 25 fractions of 2 Gy delivered to the planning target volume. HDN shaped as cylinders with a 1 cm diameter and 1 cm height were placed within the gross tumour volume. The number of HDNs and their position were determined based on tumor size and proximity to organs at risk. Three patients were irradiated using the LRT technique.

AB - This work demonstrates the safety and feasibility of Lattice Radiotherapy (LRT) for large soft tissue sarcoma in neoadjuvant radiotherapy. The treatment consisted of two courses: the LRT course with a single fraction of 20 Gy delivered to high dose nuclei (HDN) regions and the conventional course with 25 fractions of 2 Gy delivered to the planning target volume. HDN shaped as cylinders with a 1 cm diameter and 1 cm height were placed within the gross tumour volume. The number of HDNs and their position were determined based on tumor size and proximity to organs at risk. Three patients were irradiated using the LRT technique.

KW - GRID

KW - LRT

KW - SFRT

KW - Soft tissue sarcoma

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DO - 10.1016/j.phro.2022.04.010

M3 - Article

AN - SCOPUS:85129687092

SN - 2405-6316

VL - 22

SP - 63

EP - 66

JO - Physics and Imaging in Radiation Oncology

JF - Physics and Imaging in Radiation Oncology

ER -

Physical aspects of a spatially fractionated radiotherapy technique for large soft tissue sarcomas

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

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