Phylogenetic inference from restriction endonuclease cleavage site maps with particular reference to the evolution of humans and the apes.

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Abstract

The estimation procedure utilizes a compatibility analysis between enzyme data sets of the most parsimonious trees constructed from the restriction enzyme. Next, a non-parametric test is given for comparing alternative phylogenies. A 2nd non-parametric test is developed for testing the molecular clock hypothesis. To illustrate the power of these procedures, data derived from the mitochondrial DNA and globin DNA of man and the apes are analyzed. Although previous analyses of these data led to the speculation that 10 times more information would be required to resolve the evolutionary relationships between man with chimps and gorillas, this algorithm resolved these relationships at the 5% level of significance. The molecular clock hypothesis was rejected at the 1% level. The implications of this phylogenetic inference when coupled with other types of data lead to the conclusion that knuckle-walking - not bipedalism - is the evolutionary novelty in mode of locomotion in the primates and that many other hominid features are primitive whereas their African ape counterparts are derived.-from Author

Original languageEnglish
Pages (from-to)221-244
Number of pages24
JournalEvolution
Volume37
Issue number2
DOIs
StatePublished - 1983

ASJC Scopus subject areas

  • General Agricultural and Biological Sciences
  • Genetics
  • Ecology, Evolution, Behavior and Systematics

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