Photopigments and circadian systems of vertebrates

Sharleen M. Argamaso; Allan C. Froehlich; Maureen A. McCall; Eviatar Nevo; Ignacio Provencio; Russell G. Foster

doi:10.1016/0301-4622(95)00009-M

Photopigments and circadian systems of vertebrates

Sharleen M. Argamaso, Allan C. Froehlich, Maureen A. McCall, Eviatar Nevo, Ignacio Provencio, Russell G. Foster

Department of Evolutionary and Environmental Biology

Research output: Contribution to journal › Article › peer-review

Abstract

In the retinal degeneration (rd) mouse the absence of rod cells and the progressive loss of cones does not result in a decrease in circadian phase shifting responses to light. By contrast, rd/rd mice are unable to perform simple visual tasks. In addition, rodless transgenic mice, and mice homozygous for the retinal degeneration slow (rds) mutation, show unattenuated circadian responses to light. Collectively these data suggest that cone cells lacking outer segments are sufficient to maintain normal circadian responses to light, or some unidentified photoreceptor within the retina. An action spectrum for circadian responses to light in rd/rd mice, and molecular analysis of retinally degenerate mice and blind mole rat eyes, suggests the involvement of a mid-to-long wavelength sensitive cone opsin in photoentrainment. Extraocular photoreceptors of non-mammalian vertebrates are currently being analyzed in order to identify functional and evolutionary similarities between visual and non-visual photoreceptor systems.

Original language	English
Pages (from-to)	3-11
Number of pages	9
Journal	Biophysical Chemistry
Volume	56
Issue number	1-2
DOIs	https://doi.org/10.1016/0301-4622(95)00009-M
State	Published - 1995

Bibliographical note

Funding Information:
These studies are being supported by AFOSR, NIMH, the Center for Cellular and Molecular Studies in Reproduction (NIH P30-289341, and by the NSF and Technology Center for Biological Timing to RGF and by the Israeli Discount Bank Chair of Evolutionary Biology and the Ancell-Teicher Research Foundation for Genetics and Molecular Evolution established by Florence and Theodore Baum-ritter of New York to EN. We thank Bobby Soni for the donation of the universal cone primers and Elizabeth Downes for editorial comments.

Keywords

CSF-contacting neurons
Circadian photoreception
Extraretinal photoreception
Opsin
Retinal degeneration

ASJC Scopus subject areas

Biophysics
Biochemistry
Organic Chemistry

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10.1016/0301-4622(95)00009-M

Cite this

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title = "Photopigments and circadian systems of vertebrates",

abstract = "In the retinal degeneration (rd) mouse the absence of rod cells and the progressive loss of cones does not result in a decrease in circadian phase shifting responses to light. By contrast, rd/rd mice are unable to perform simple visual tasks. In addition, rodless transgenic mice, and mice homozygous for the retinal degeneration slow (rds) mutation, show unattenuated circadian responses to light. Collectively these data suggest that cone cells lacking outer segments are sufficient to maintain normal circadian responses to light, or some unidentified photoreceptor within the retina. An action spectrum for circadian responses to light in rd/rd mice, and molecular analysis of retinally degenerate mice and blind mole rat eyes, suggests the involvement of a mid-to-long wavelength sensitive cone opsin in photoentrainment. Extraocular photoreceptors of non-mammalian vertebrates are currently being analyzed in order to identify functional and evolutionary similarities between visual and non-visual photoreceptor systems.",

keywords = "CSF-contacting neurons, Circadian photoreception, Extraretinal photoreception, Opsin, Retinal degeneration",

author = "Argamaso, {Sharleen M.} and Froehlich, {Allan C.} and McCall, {Maureen A.} and Eviatar Nevo and Ignacio Provencio and Foster, {Russell G.}",

note = "Funding Information: These studies are being supported by AFOSR, NIMH, the Center for Cellular and Molecular Studies in Reproduction (NIH P30-289341, and by the NSF and Technology Center for Biological Timing to RGF and by the Israeli Discount Bank Chair of Evolutionary Biology and the Ancell-Teicher Research Foundation for Genetics and Molecular Evolution established by Florence and Theodore Baum-ritter of New York to EN. We thank Bobby Soni for the donation of the universal cone primers and Elizabeth Downes for editorial comments.",

year = "1995",

doi = "10.1016/0301-4622(95)00009-M",

language = "English",

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pages = "3--11",

journal = "Biophysical Chemistry",

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AU - Froehlich, Allan C.

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AU - Provencio, Ignacio

AU - Foster, Russell G.

N1 - Funding Information: These studies are being supported by AFOSR, NIMH, the Center for Cellular and Molecular Studies in Reproduction (NIH P30-289341, and by the NSF and Technology Center for Biological Timing to RGF and by the Israeli Discount Bank Chair of Evolutionary Biology and the Ancell-Teicher Research Foundation for Genetics and Molecular Evolution established by Florence and Theodore Baum-ritter of New York to EN. We thank Bobby Soni for the donation of the universal cone primers and Elizabeth Downes for editorial comments.

PY - 1995

Y1 - 1995

N2 - In the retinal degeneration (rd) mouse the absence of rod cells and the progressive loss of cones does not result in a decrease in circadian phase shifting responses to light. By contrast, rd/rd mice are unable to perform simple visual tasks. In addition, rodless transgenic mice, and mice homozygous for the retinal degeneration slow (rds) mutation, show unattenuated circadian responses to light. Collectively these data suggest that cone cells lacking outer segments are sufficient to maintain normal circadian responses to light, or some unidentified photoreceptor within the retina. An action spectrum for circadian responses to light in rd/rd mice, and molecular analysis of retinally degenerate mice and blind mole rat eyes, suggests the involvement of a mid-to-long wavelength sensitive cone opsin in photoentrainment. Extraocular photoreceptors of non-mammalian vertebrates are currently being analyzed in order to identify functional and evolutionary similarities between visual and non-visual photoreceptor systems.

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Photopigments and circadian systems of vertebrates

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

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