Patient mood flux on- and off-hemodialysis

Micah Leshem, Wisam Sliman, Souzan Taweel, Rana Shamshoum, Zaher Armaly

Research output: Contribution to journalArticlepeer-review


Mood in hemodialysis patients is most often evaluated off-dialysis, possibly underestimating mood during dialysis. We compared mood in patients on- and off-dialysis using the Positive and Negative Affect Schedule for 6 consecutive days. Initially, scores are normal, but subsequently positive affect falls below, and negative affect increases above, off-dialysis values, suggesting increasing depression and anxiety, particularly in women. Quality-of-life questions confirm the effects of the dialysis session on mood. Prevalence and severity of depression evaluated off-dialysis, or once only, may be underestimated, especially in women, because hemodialysis patients undergo mood swings centering on the dialysis session. Focusing insight on the dialysis session could improve coping among patients and caretakers.

Original languageEnglish
Pages (from-to)488-494
Number of pages7
JournalHemodialysis International
Issue number2
StatePublished - Apr 2014

Bibliographical note

Funding Information:
The research in the author’s laboratory is funded by Canadian Forest Service Genomics and British Columbia Forest Innovation Investment Account. Dr. A.K.M. Ekramoddoullah thanks various team members in his laboratory, whose dedicated work over the years helped him to write this paper, and Ms. M. Keiran for editing the manuscript.


  • Anxiety
  • Depression
  • Gender
  • Hemodialysis session
  • Mood

ASJC Scopus subject areas

  • Hematology
  • Nephrology


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