Ontogeny of the ionic specificity of sodium appetite in the rat pup

Micah Leshem; Michal Neufeld; Sonia Del Canho

doi:10.1002/dev.420270606

Ontogeny of the ionic specificity of sodium appetite in the rat pup

Micah Leshem, Michal Neufeld, Sonia Del Canho

Department of Psychology

Research output: Contribution to journal › Article › peer-review

Abstract

Sodium‐deficient adult rats prefer NaCl to other monochloride salts (e.g., Denton, 1991; Schulkin, 1991). However, it is not known when or how this specificity develops. Our experiments charted the development of the ionic specificity of sodium appetite aroused by sodium depletion or intracerebroventricular injection of renin. We compared intake of 3% NaCl to three other monochlorides, potassium (K), ammonium (NH₄), and lithium (Li), and calcium chloride (CaCl₂) at various ages between 72 hr postnatal and weaning. This revealed a biphasic developmental scheme: The adult pattern of discrimination between the salts emerges between 3 and 18 days of age. Subsequently, the preference for Na over the other salts increases into adulthood.©1994 John Wiley & Sons, Inc.

Original language	English
Pages (from-to)	381-394
Number of pages	14
Journal	Developmental Psychobiology
Volume	27
Issue number	6
DOIs	https://doi.org/10.1002/dev.420270606
State	Published - Sep 1994

ASJC Scopus subject areas

Developmental and Educational Psychology
Developmental Neuroscience
Developmental Biology
Behavioral Neuroscience

Access to Document

10.1002/dev.420270606

Cite this

@article{1e0212ef082943d8a1d0f6a7fbb39d4a,

title = "Ontogeny of the ionic specificity of sodium appetite in the rat pup",

abstract = "Sodium‐deficient adult rats prefer NaCl to other monochloride salts (e.g., Denton, 1991; Schulkin, 1991). However, it is not known when or how this specificity develops. Our experiments charted the development of the ionic specificity of sodium appetite aroused by sodium depletion or intracerebroventricular injection of renin. We compared intake of 3% NaCl to three other monochlorides, potassium (K), ammonium (NH4), and lithium (Li), and calcium chloride (CaCl2) at various ages between 72 hr postnatal and weaning. This revealed a biphasic developmental scheme: The adult pattern of discrimination between the salts emerges between 3 and 18 days of age. Subsequently, the preference for Na over the other salts increases into adulthood.{\textcopyright}1994 John Wiley & Sons, Inc.",

author = "Micah Leshem and Michal Neufeld and Canho, {Sonia Del}",

year = "1994",

month = sep,

doi = "10.1002/dev.420270606",

language = "English",

volume = "27",

pages = "381--394",

journal = "Developmental Psychobiology",

issn = "0012-1630",

publisher = "John Wiley and Sons Inc.",

number = "6",

}

TY - JOUR

T1 - Ontogeny of the ionic specificity of sodium appetite in the rat pup

AU - Leshem, Micah

AU - Neufeld, Michal

AU - Canho, Sonia Del

PY - 1994/9

Y1 - 1994/9

N2 - Sodium‐deficient adult rats prefer NaCl to other monochloride salts (e.g., Denton, 1991; Schulkin, 1991). However, it is not known when or how this specificity develops. Our experiments charted the development of the ionic specificity of sodium appetite aroused by sodium depletion or intracerebroventricular injection of renin. We compared intake of 3% NaCl to three other monochlorides, potassium (K), ammonium (NH4), and lithium (Li), and calcium chloride (CaCl2) at various ages between 72 hr postnatal and weaning. This revealed a biphasic developmental scheme: The adult pattern of discrimination between the salts emerges between 3 and 18 days of age. Subsequently, the preference for Na over the other salts increases into adulthood.©1994 John Wiley & Sons, Inc.

AB - Sodium‐deficient adult rats prefer NaCl to other monochloride salts (e.g., Denton, 1991; Schulkin, 1991). However, it is not known when or how this specificity develops. Our experiments charted the development of the ionic specificity of sodium appetite aroused by sodium depletion or intracerebroventricular injection of renin. We compared intake of 3% NaCl to three other monochlorides, potassium (K), ammonium (NH4), and lithium (Li), and calcium chloride (CaCl2) at various ages between 72 hr postnatal and weaning. This revealed a biphasic developmental scheme: The adult pattern of discrimination between the salts emerges between 3 and 18 days of age. Subsequently, the preference for Na over the other salts increases into adulthood.©1994 John Wiley & Sons, Inc.

UR - http://www.scopus.com/inward/record.url?scp=0028508042&partnerID=8YFLogxK

U2 - 10.1002/dev.420270606

DO - 10.1002/dev.420270606

M3 - Article

C2 - 8001727

AN - SCOPUS:0028508042

SN - 0012-1630

VL - 27

SP - 381

EP - 394

JO - Developmental Psychobiology

JF - Developmental Psychobiology

IS - 6

ER -

Ontogeny of the ionic specificity of sodium appetite in the rat pup

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this