TY - JOUR
T1 - Ongoing tuberculosis transmission among second-generation Ethiopian immigrants in Israel
AU - Bishara, H.
AU - Green, M.
AU - Chemtob, D.
AU - Saffouri, A.
AU - Zelikman, L.
AU - Weiler-Ravell, D.
N1 - Publisher Copyright:
© 2020 Cambridge University Press. All rights reserved.
PY - 2020/8/3
Y1 - 2020/8/3
N2 - Despite considerable efforts to control tuberculosis (TB) among Ethiopian immigrants in Israel, an outbreak of TB among second-generation Ethiopian immigrants that also involved native Israelis occurred between January 2011 and December 2019. The aim of this article is to report on this outbreak and discuss the patient and health system barriers that led to its propagation. Overall, thirteen culture-positive TB patients were diagnosed in this outbreak. An additional 36 cases with identical mycobacterium tuberculosis genotypes were identified through cross-checking with the National TB Laboratory Registry. Among the 32 close contacts of the index case, 18 (56.3%) reported for screening, and treatment of latent TB infection (LTBI) was recommended for 11 (61.1%) of them. However, none completed treatment, and eight eventually developed TB. Of the 385 close contacts identified in this outbreak, 286 (74%) underwent contact investigation, 154 (53.8%) were recommended LTBI treatment, but only 26 (16.9%) completed the treatment. Routine contact investigation and treatment practice measures failed to contain the cascade of infection and disease, leading to the spread of the infecting strain of TB. This report highlight the challenges to identify high-risk group and address barriers to care among such vulnerable population.
AB - Despite considerable efforts to control tuberculosis (TB) among Ethiopian immigrants in Israel, an outbreak of TB among second-generation Ethiopian immigrants that also involved native Israelis occurred between January 2011 and December 2019. The aim of this article is to report on this outbreak and discuss the patient and health system barriers that led to its propagation. Overall, thirteen culture-positive TB patients were diagnosed in this outbreak. An additional 36 cases with identical mycobacterium tuberculosis genotypes were identified through cross-checking with the National TB Laboratory Registry. Among the 32 close contacts of the index case, 18 (56.3%) reported for screening, and treatment of latent TB infection (LTBI) was recommended for 11 (61.1%) of them. However, none completed treatment, and eight eventually developed TB. Of the 385 close contacts identified in this outbreak, 286 (74%) underwent contact investigation, 154 (53.8%) were recommended LTBI treatment, but only 26 (16.9%) completed the treatment. Routine contact investigation and treatment practice measures failed to contain the cascade of infection and disease, leading to the spread of the infecting strain of TB. This report highlight the challenges to identify high-risk group and address barriers to care among such vulnerable population.
UR - http://www.scopus.com/inward/record.url?scp=85090077601&partnerID=8YFLogxK
U2 - 10.1017/S0950268820001715
DO - 10.1017/S0950268820001715
M3 - Article
C2 - 32741390
AN - SCOPUS:85090077601
SN - 0950-2688
JO - Epidemiology and Infection
JF - Epidemiology and Infection
ER -