TY - JOUR
T1 - New patient-oriented diagnostic test characteristics analogous to the likelihood ratios conveyed information on trustworthiness
AU - Linn, Shai
PY - 2005/5
Y1 - 2005/5
N2 - Objective: Suggesting patient-oriented ratio measures of diagnostic tests analogous to the likelihood ratios. Study Design and Setting: Algebraic equation based on Bayes' theorem. Results: Two new measures are suggested: the positive predictive ratio (PPR), relating the positive predictive value (PPV) to the false negative rate in the patient population, and the negative predictive ratio (NPR), relating the negative predictive value (NPV) to the false positive rate in the patient population. The new measures are analogous to likelihood ratios. These measures are calculable from the familiar 2×2 table in a selected study population or in a target (general) population. Examples are given, using published data. Conclusion: PPR adds to the information given by the PPV, and NPR adds to the information given by the NPV. PPR and NPR may be more appropriate in the clinical setting than likelihood ratios.
AB - Objective: Suggesting patient-oriented ratio measures of diagnostic tests analogous to the likelihood ratios. Study Design and Setting: Algebraic equation based on Bayes' theorem. Results: Two new measures are suggested: the positive predictive ratio (PPR), relating the positive predictive value (PPV) to the false negative rate in the patient population, and the negative predictive ratio (NPR), relating the negative predictive value (NPV) to the false positive rate in the patient population. The new measures are analogous to likelihood ratios. These measures are calculable from the familiar 2×2 table in a selected study population or in a target (general) population. Examples are given, using published data. Conclusion: PPR adds to the information given by the PPV, and NPR adds to the information given by the NPV. PPR and NPR may be more appropriate in the clinical setting than likelihood ratios.
KW - Bayes' theorem
KW - Clinical
KW - Diagnosis
KW - Patients
KW - Predictive value
KW - Test
UR - http://www.scopus.com/inward/record.url?scp=17444412728&partnerID=8YFLogxK
U2 - 10.1016/j.jclinepi.2004.07.009
DO - 10.1016/j.jclinepi.2004.07.009
M3 - Article
C2 - 15845331
AN - SCOPUS:17444412728
SN - 0895-4356
VL - 58
SP - 450
EP - 457
JO - Journal of Clinical Epidemiology
JF - Journal of Clinical Epidemiology
IS - 5
ER -