Neuroimages in Autism

Rafael Rodríguez-Rojas, Calixto Machado, Karla Batista, Maylen Carballo, Gerry Leisman

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


This chapter summarizes findings of the morphological and functional brain changes in autistic spectrum disorders (ASD), demonstrated by a growing body of researches that employs diverse neuroimaging methods. We discuss major anatomical findings from studies in ASD utilizing structural magnetic resonance imaging (MRI) and diffusion tensor imaging (DTI). We also explore findings from functional MRI (fMRI) studies, including task–related activation studies and functional connectivity. Regional changes in brain metabolism are examined using magnetic resonance spectroscopy (MRS) and nuclear medicine techniques, including positron emission tomography (PET) and single–photon emission tomography (SPECT). Finally, we highlight directions for continued research in neuroimaging of ASD at a network level using graph theoretical approaches.

Original languageEnglish
Title of host publicationTranslational Approaches to Autism Apectrum Disorder
PublisherSpringer International Publishing
Number of pages23
ISBN (Electronic)9783319163215
ISBN (Print)9783319163208
StatePublished - 1 Jan 2015
Externally publishedYes

Bibliographical note

Publisher Copyright:
© Springer International Publishing Switzerland 2015.


  • ASD
  • Connectivity
  • Diffusion tensor imaging
  • Emission tomography
  • Magnetic resonance imaging
  • Spectroscopy

ASJC Scopus subject areas

  • General Medicine
  • General Neuroscience


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