Objectives: A patient's personal interpretations of a health threat or "illness perceptions" (IPs) are associated with their clinical outcomes. This study explored whether IPs are associated with pain severity and ability to modulate pain in women with chronic pelvic pain syndrome (CPPS), as well as the predictive value of IPs on myofascial manual therapy (MMT) success. Materials and Methods: Illness Perceptions Questionnaire-Revised (IPQ-R), mechanical and heat pain thresholds, mechanical temporal summation, and conditioned pain modulation (CPM) were evaluated in CPPS patients (n=39) before, and 3 months after MMT. CPPS severity was obtained by the Brief Pain Inventory (BPI). Results: Stronger perceptions of illness chronicity were correlated with less efficient CPM (r=0.488, P=0.002) and increased mechanical pain intensity (r=0.405, P=0.02). Lower perceptions of control over illness were associated with enhanced mechanical temporal summation (r=0.399, P=0.01). Higher BPI scores were correlated with emotional representations (negative emotional representations) and severe consequences due to CPPS. Regression analyses revealed that negative IPs predict less efficient MMT. Discussion: Cognitive representations play a unique role in CPPS expression and MMT outcomes. The interplay between negative IPs and a pronociceptive modulation profile, mediated by enhanced facilitatory and reduced inhibitory processes, may be involved in the manifestation of CPPS.
|Number of pages||8|
|Journal||Clinical Journal of Pain|
|State||Published - 1 Dec 2018|
Bibliographical noteFunding Information:
This study was sponsored by the Israeli Ministry of Health Grant, Jerusalem, Israel (300000-7495) and the Israel Pain Association, Tel-Aviv, Israel. The authors declare no conflict of interest.
Copyright © 2018 Wolters Kluwer Health, Inc. All rights reserved.
- Key Words: illness perceptions
- chronic pelvic pain syndrome
- conditioned pain modulation
- myofascial manual therapy
ASJC Scopus subject areas
- Clinical Neurology
- Anesthesiology and Pain Medicine