Multidrug-Resistant Tuberculosis

Jeffrey P. Nadler, Noya Galai, Neil Graham, Richard Chaisson, Kenrad E. Nelson, David Vlahov, John Lewis, Edward A. Nardell, Michael D. Iseman, George Kubica, Richard L. Riley, William W. Stead, Fredrick Urbach, Brian R. Edlin, Jerome I. Tokars, Kenneth G. Castro, Samuel W. Dooley

Research output: Contribution to journalLetterpeer-review


To the Editor: Edlin et al. (June 4 issue)* ascribe the transmission of multidrug-resistant tuberculosis to patient-to-patient spread, on the basis of their epidemiologic study. In their discussion, they note that tuberculin-skin-test conversions occurred in 18 percent of health care workers, and that one worker had resistant tuberculosis whose pattern of restriction-fragmentlength polymorphisms matched that of the case isolates. More details are needed about the epidemiologic association between the patients and the workers with skin-test conversions, especially the worker with tuberculosis. What are the temporal relations? Person-to-person spread involving the infected health care worker is not excluded by the data…

Original languageEnglish
Pages (from-to)1172-1174
Number of pages3
JournalNew England Journal of Medicine
Issue number16
StatePublished - 15 Oct 1992
Externally publishedYes

ASJC Scopus subject areas

  • General Medicine


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