Minimal-dot plot: "old tale in new skin" about sequence comparison

V. Kirzhner, S. Frenkel, A. Korol

Research output: Contribution to journalArticlepeer-review


The authors propose a simple version of the dot-plot scheme to be used in the case when the distances between sequence elements may take more than two values. The method is applicable, in particular, to the case of the sequences of large-length windows when the sets of distance values are continuous. The proposed technique is simple to implement and the results can produce readable maps for further analysis. To illustrate its potentialities, the method has been applied to the comparison of genomic sequences. The asymmetry in the number of direct and reverse tracks for the Homo sapience genome has been discovered.

Original languageEnglish
Pages (from-to)1454-1462
Number of pages9
JournalInformation Sciences
Issue number8
StatePublished - 15 Apr 2011


  • Compositional spectra
  • Dot-plot
  • Human genome
  • Sequence comparison
  • Track asymmetry

ASJC Scopus subject areas

  • Software
  • Control and Systems Engineering
  • Theoretical Computer Science
  • Computer Science Applications
  • Information Systems and Management
  • Artificial Intelligence


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