Messenger RNA Translation Defects in Neurodegenerative Diseases.

Erik Storkebaum, Kobi Rosenblum, Nahum Sonenberg

Research output: Contribution to journalArticlepeer-review

Abstract

Translation Defects in Neurodegenerative Diseases Aberrant mRNA translation is a prominent feature in many neurodegenerative diseases. The pathological hallmark is abnormally folded protein aggregates, with a unique molecular composition.

Original languageEnglish
Pages (from-to)1015-1030
Number of pages16
JournalNew England Journal of Medicine
Volume388
Issue number11
DOIs
StatePublished - 16 Mar 2023

Bibliographical note

Publisher Copyright:
© 2023 Massachusetts Medical Society.

Keywords

  • Amyotrophic Lateral Sclerosis
  • Dementia/Alzheimer Disease
  • Genetics
  • Neurology/Neurosurgery
  • Neuromuscular Disease
  • Neuroscience
  • Parkinson Disease

ASJC Scopus subject areas

  • General Medicine

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