Medicinal mushrooms: Valuable biological resources of high exploitation potential

Maria Letizia Gargano, Leo J.L.D. van Griensven, Omoanghe S. Isikhuemhen, Ulrike Lindequist, Giuseppe Venturella, Solomon P. Wasser, Georgios I. Zervakis

Research output: Contribution to journalReview articlepeer-review


Higher Basidiomycetes and Ascomycetes mushrooms possess various immunological and anticancer properties. They also offer important health benefits and exhibit a broad spectrum of pharmacological activities including antibacterial, antifungal, antiviral, cytotoxic, immunomodulating, anti-inflammatory, antioxidative, antiallergic, antidepressive, antihyperlipidemic, antidiabetic, digestive, hepatoprotective, neuroprotective, nephroprotective, osteoprotective, and hypotensive activities. This minireview summarizes the perspectives, recent advances, and major challenges of medicinal mushrooms with reference to their nutraceutical properties and dietary value, the production of mushroom biomass on various substrates, and the purification, characterization, and pharmaceutical effects of biologically active compounds from medicinal mushrooms.

Original languageEnglish
Pages (from-to)548-565
Number of pages18
JournalPlant Biosystems
Issue number3
StatePublished - 4 May 2017

Bibliographical note

Publisher Copyright:
© 2017 Società Botanica Italiana.


  • Medicinal mushrooms
  • active compounds
  • dietary value
  • fungal biomass
  • mushrooms cultivation
  • nutraceutical properties

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Plant Science


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