LTP in the rat basal amygdala induced by perirhinal cortex stimulation in vivo

Research output: Contribution to journalArticlepeer-review


The present study examined the effects of ventral perirhinal cortex (vPRC) stimulation on evoked field potentials (EPs) in the basal amygdala (BN), using extracellular recording techniques. Single pulse stimulation of the vPRC reliably evoked a negative field potential in the BN that was missing in the lateral nucleus. Paired-pulses delivered to the vPRC induced a short-lasting facilitation at intervals between 15 and 120 ms. Application of brief theta burst stimulation to the vPRC produced an enduring long-term potentiation (LTP) that reached 150% of control values. The induction of LTP was not accompanied by a decrease in paired-pulse facilitation. These results suggest that emotional learning involving complex stimulus representations may be mediated by cortico-amygdalar projections amenable to LTP. (C) 2000 Lippincott Williams and Wilkins.

Original languageEnglish
Pages (from-to)525-530
Number of pages6
Issue number3
StatePublished - 2000


  • Amygdala
  • Emotion
  • Fear
  • LTP
  • Memory
  • Paired-pulse
  • Perirhinal cortex

ASJC Scopus subject areas

  • General Neuroscience


Dive into the research topics of 'LTP in the rat basal amygdala induced by perirhinal cortex stimulation in vivo'. Together they form a unique fingerprint.

Cite this