LSD-Induced hallucinogen persisting perception disorder treated with clonazepam: Two case reports

Arturo G. Lerner, Irena Skladman, Arad Kodesh, Mircea Sigal, Emi Shufman

Research output: Contribution to journalArticlepeer-review

Abstract

Benzodiazepines are recommended for the treatment of Hallucinogen Persisting Perception Disorder (HPPD), although it is unclear which may be more helpful. Two out-patients with LSD-induced HPPD were successfully treated with clonazepam. They had not responded to low potency benzodiazepines or low doses of classic antipsychotics. After clonazepam discontinuation they reported a marked improvement and only mild symptomatology which persisted during a six month follow-up period. High potency benzodiazepines like clonazepam, which has serotonergic properties, may be superior to low-potency benzodiazepines in the treatment of some patients with LSD-induced HPPD.

Original languageEnglish
Pages (from-to)133-136
Number of pages4
JournalIsrael Journal of Psychiatry and Related Sciences
Volume38
Issue number2
StatePublished - 2001
Externally publishedYes

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

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