Low threshold calcium spikes in medial vestibular nuclei neurones in vitro: a role in the generation of the vestibular nystagmus quick phase in vivo?

M. Serafin, A. Khateb, C. de Waele, P. P. Vidal, M. Mühlethaler

Research output: Contribution to journalArticlepeer-review

Abstract

Intracellular recordings were obtained from medial vestibular nuclei neurones in guinea-pig brainstem slices. A subpopulation of neurones in this nucleus was found to have burst firing properties. Using ionic channel blockers the underlying mechanism was shown to be a low threshold calcium spike. It is speculated that this property could be implicated in the generation of the quick phase of the vestibular nystagmus in the behaving guinea-pig.

Original languageEnglish
Pages (from-to)187-190
Number of pages4
JournalExperimental Brain Research
Volume82
Issue number1
DOIs
StatePublished - Aug 1990
Externally publishedYes

Keywords

  • Calcium conductances
  • Eye movements
  • Guinea-pig

ASJC Scopus subject areas

  • Neuroscience (all)

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