Low threshold calcium spikes in medial vestibular nuclei neurones in vitro: a role in the generation of the vestibular nystagmus quick phase in vivo?

M. Serafin; A. Khateb; C. de Waele; P. P. Vidal; M. Mühlethaler

doi:10.1007/BF00230850

Low threshold calcium spikes in medial vestibular nuclei neurones in vitro: a role in the generation of the vestibular nystagmus quick phase in vivo?

M. Serafin, A. Khateb, C. de Waele, P. P. Vidal, M. Mühlethaler

Research output: Contribution to journal › Article › peer-review

Abstract

Intracellular recordings were obtained from medial vestibular nuclei neurones in guinea-pig brainstem slices. A subpopulation of neurones in this nucleus was found to have burst firing properties. Using ionic channel blockers the underlying mechanism was shown to be a low threshold calcium spike. It is speculated that this property could be implicated in the generation of the quick phase of the vestibular nystagmus in the behaving guinea-pig.

Original language	English
Pages (from-to)	187-190
Number of pages	4
Journal	Experimental Brain Research
Volume	82
Issue number	1
DOIs	https://doi.org/10.1007/BF00230850
State	Published - Aug 1990
Externally published	Yes

Keywords

Calcium conductances
Eye movements
Guinea-pig

ASJC Scopus subject areas

General Neuroscience

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/BF00230850

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abstract = "Intracellular recordings were obtained from medial vestibular nuclei neurones in guinea-pig brainstem slices. A subpopulation of neurones in this nucleus was found to have burst firing properties. Using ionic channel blockers the underlying mechanism was shown to be a low threshold calcium spike. It is speculated that this property could be implicated in the generation of the quick phase of the vestibular nystagmus in the behaving guinea-pig.",

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AU - Vidal, P. P.

AU - Mühlethaler, M.

PY - 1990/8

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N2 - Intracellular recordings were obtained from medial vestibular nuclei neurones in guinea-pig brainstem slices. A subpopulation of neurones in this nucleus was found to have burst firing properties. Using ionic channel blockers the underlying mechanism was shown to be a low threshold calcium spike. It is speculated that this property could be implicated in the generation of the quick phase of the vestibular nystagmus in the behaving guinea-pig.

AB - Intracellular recordings were obtained from medial vestibular nuclei neurones in guinea-pig brainstem slices. A subpopulation of neurones in this nucleus was found to have burst firing properties. Using ionic channel blockers the underlying mechanism was shown to be a low threshold calcium spike. It is speculated that this property could be implicated in the generation of the quick phase of the vestibular nystagmus in the behaving guinea-pig.

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KW - Eye movements

KW - Guinea-pig

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Low threshold calcium spikes in medial vestibular nuclei neurones in vitro: a role in the generation of the vestibular nystagmus quick phase in vivo?

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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