Leveraging nematocysts toward human care

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


The stinging cells of cnidarians contain nematocysts, which are a sophisticated ultra-fast injection system that can penetrate the skin immediately. This chapter will review two nematocyst-based biotechnology applications. The first hinders nematocyst discharge and thereby prevents jellyfish envenomation. The development of the inhibitory formulation and the demonstration of its effectiveness by clinical trials will be described. The second application utilizes isolated nematocysts as micro-devices for active drug delivery. The advantages of this novel approach will be demonstrated by the results of in vitro and in vivo pharmacokinetics studies.

Original languageEnglish
Title of host publicationThe Cnidaria, past, present and Future
Subtitle of host publicationThe World of Medusa and her Sisters
PublisherSpringer International Publishing
Number of pages8
ISBN (Electronic)9783319313054
ISBN (Print)9783319313030
StatePublished - 1 Jan 2016

Bibliographical note

Publisher Copyright:
© Springer International Publishing Switzerland 2016.


  • Active transdermal drug delivery
  • Jellyfish envenomation
  • Micro drug device
  • Nematocyst discharge
  • Sting inhibition

ASJC Scopus subject areas

  • Agricultural and Biological Sciences (all)
  • Environmental Science (all)
  • Earth and Planetary Sciences (all)


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