Laboratory Test of a Novel Structural Model of Anxiety Sensitivity and Panic Vulnerability

Amit Bernstein, Michael J. Zvolensky, Michael J. Zvolensky, Norman B. Schmidt

Research output: Contribution to journalArticlepeer-review


The current study evaluated a novel latent structural model of anxiety sensitivity (AS) in relation to panic vulnerability among a sample of young adults (N = 216). AS was measured using the 16-item Anxiety Sensitivity Index (ASI; Reiss, Peterson, Gursky, & McNally, 1986), and panic vulnerability was indexed by panic attack responding to a single administration of a 4-minute, 10% CO2 challenge. As predicted, vulnerability for panic attack responding to biological challenge was associated with dichotomous individual differences between taxonic AS classes and continuous within-taxon class individual differences in AS physical concerns. Findings supported the AS taxonic-dimensional hypothesis of AS latent structure and panic vulnerability. These findings are discussed in terms of their theoretical and clinical implications.

Original languageEnglish
Pages (from-to)171-180
Number of pages10
JournalBehavior Therapy
Issue number2
StatePublished - Jun 2009

ASJC Scopus subject areas

  • Clinical Psychology


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