Isolated large fourth ventricle in early pregnancy: A possible benign transient phenomenon

M. Bronshtein, E. Z. Zimmer, S. Blazer

Research output: Contribution to journalArticlepeer-review

Abstract

Twenty-one fetuses with an enlarged fourth ventricle were detected by ultrasound at 14-16 weeks' gestation. No other central nervous system anomalies were observed and a normal size fourth ventricle was noted in all cases on follow-up scans at 22-23 weeks' gestation. Five fetuses had associated structural anomalies: a single umbilical artery in two cases, non-septated cystic hygroma in two cases and ventricular septal defect in one fetus. All fetuses had a normal brain sonogram after delivery. Nineteen newborns who were followed up to the age of one year had no developmental problems. It is concluded that an isolated enlarged fourth ventricle might be a physiological variant in early fetal life.

Original languageEnglish
Pages (from-to)997-1000
Number of pages4
JournalPrenatal Diagnosis
Volume18
Issue number10
DOIs
StatePublished - 1998
Externally publishedYes

Keywords

  • Early pregnancy
  • Fetus
  • Fourth ventricle
  • Ultrasonography

ASJC Scopus subject areas

  • Genetics(clinical)
  • Obstetrics and Gynecology

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