Is Use Of Sedative-Hypnotics During Hospitalization Associated With Adverse Functional Outcomes?

Research output: Contribution to journalMeeting Abstract


More than one-quarter of hospitalized older adults consume sedative-hypnotics, but their adverse effects on mobility and function during hospitalization are unknown. We will present results of a prospective cohort study of 177 adults which examined the effects of sedative-hypnotic consumption on in-hospital mobility and functional decline. A daily step count was monitored using an Actical monitor, and function was assessed at admission and discharge using objective and subjective indexes. Patients consuming sedative-hypnotics (28.7%, n=50) were significantly less mobile than patients who did not use these drugs (mean step count 1400 (SD 1620) vs 2200 (SD 2328), p=0.023). However, after controlling for age and basic functioning the difference between groups was not significant. Additionally, sedative-hypnotic consumption was not significantly associated with changes in functional outcomes. We will discuss future steps for research in this area, including the influence of different hypnotic drugs’ groups as well as their sedative load
Original languageEnglish
Pages (from-to)1242
Number of pages1
JournalInnovation in Aging
Issue numberSuppl 1
StatePublished - 2017
Event21st International Association of Gerontology and Geriatrics (IAGG) World Congress - Moscone West San Francisco, San Francisco, United States
Duration: 23 Jul 201727 Jul 2017


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