Introduction to Functional Magnetic Resonance Imaging: Understanding the Measured Signal

Pia Rotshtein, Charumati Raghavan

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


The introduction to functional Magnetic Resonance Imaging (fMRI) article provides a description of the fMRI measurement and its neurobiological meaning. It starts by describing the principle of the MRI scanner focusing on the parts that are relevant to fMRI data. fMRI data measures changes of oxygen concentration in the blood, utilizing the Blood Oxygen Level Dependent Contrast. The article then describes current understanding of neurovascular coupling, the way in which the fMRI signal is linked to neural activity.

Original languageEnglish
Title of host publicationEncyclopedia of Behavioral Neuroscience
Subtitle of host publicationVolumes 1-3, Second edition
ISBN (Electronic)9780128196410
StatePublished - 1 Jan 2021
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2021 Elsevier Ltd. All rights reserved.


  • Blood Oxygenated Level Dependent (BOLD) contrast
  • Initial dip
  • Negative BOLD

ASJC Scopus subject areas

  • General Medicine
  • General Neuroscience


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